Cell Structure and Function — Hard Practice Quiz

A Biology cheat sheet for Cell Structure and Function — every key formula with its symbols defined — plus a hard-level practice quiz to test recall.

Formulas & key concepts

The biological concept that states that all organisms are composed of one or more cells, the cell is the basic unit of life, and new cells arise from existing cells.

Unified Cell Theory

<table style='width:100%; border-collapse: collapse; font-size: 0.8em;'><tr><th style='border:1px solid #ddd; padding:4px;'>Feature</th><th style='border:1px solid #ddd; padding:4px;'>Prokaryotes</th><th style='border:1px solid #ddd; padding:4px;'>Eukaryotes</th></tr><tr><td style='border:1px solid #ddd; padding:4px;'>Nucleus</td><td style='border:1px solid #ddd; padding:4px;'>No</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'>Size</td><td style='border:1px solid #ddd; padding:4px;'>0.1–5.0 µm</td><td style='border:1px solid #ddd; padding:4px;'>10–100 µm</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'>Organelles</td><td style='border:1px solid #ddd; padding:4px;'>None</td><td style='border:1px solid #ddd; padding:4px;'>Membrane-bound</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'>Examples</td><td style='border:1px solid #ddd; padding:4px;'>Bacteria, Archaea</td><td style='border:1px solid #ddd; padding:4px;'>Animals, Plants, Fungi</td></tr></table>

Prokaryotic vs Eukaryotic Cells

<img src='prokaryotic cell.png' alt='Prokaryotic Cell' style='width:100%; max-width:400px; display:block; margin: 0 auto;'>

Prokaryotic Cell Diagram

<img src='animal cell.png' alt='Animal Cell' style='width:100%; max-width:400px; display:block; margin: 0 auto;'>

Animal Cell Diagram

<img src='plant cell.png' alt='Plant Cell' style='width:100%; max-width:400px; display:block; margin: 0 auto;'>

Plant Cell Diagram

<table style='width:100%; border-collapse: collapse; font-size: 0.8em;'><tr><th style='border:1px solid #ddd; padding:4px;'>Component</th><th style='border:1px solid #ddd; padding:4px;'>Function</th><th style='border:1px solid #ddd; padding:4px;'>Animal Cell</th><th style='border:1px solid #ddd; padding:4px;'>Plant Cell</th></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Plasma Membrane</b></td><td style='border:1px solid #ddd; padding:4px;'>Separates cell from external environment; controls passage of materials</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Cytoplasm</b></td><td style='border:1px solid #ddd; padding:4px;'>Provides structure; site of metabolic reactions</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Nucleus</b></td><td style='border:1px solid #ddd; padding:4px;'>Houses DNA; directs synthesis of ribosomes and proteins</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Ribosomes</b></td><td style='border:1px solid #ddd; padding:4px;'>Protein synthesis</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Mitochondria</b></td><td style='border:1px solid #ddd; padding:4px;'>ATP production / cellular respiration</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Peroxisomes</b></td><td style='border:1px solid #ddd; padding:4px;'>Oxidizes fatty acids/amino acids; detoxifies poisons</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Vesicles & Vacuoles</b></td><td style='border:1px solid #ddd; padding:4px;'>Storage and transport; digestive function in plants</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Centrosome</b></td><td style='border:1px solid #ddd; padding:4px;'>Role in cell division; organizing center of microtubules</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>No</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Lysosomes</b></td><td style='border:1px solid #ddd; padding:4px;'>Digestion of macromolecules; recycling of organelles</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>No</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Cell Wall</b></td><td style='border:1px solid #ddd; padding:4px;'>Protection, structural support, maintenance of shape</td><td style='border:1px solid #ddd; padding:4px;'>No</td><td style='border:1px solid #ddd; padding:4px;'>Yes (Cellulose)</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Chloroplasts</b></td><td style='border:1px solid #ddd; padding:4px;'>Photosynthesis</td><td style='border:1px solid #ddd; padding:4px;'>No</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Endoplasmic Reticulum</b></td><td style='border:1px solid #ddd; padding:4px;'>Modifies proteins and synthesizes lipids</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Golgi Apparatus</b></td><td style='border:1px solid #ddd; padding:4px;'>Modifies, sorts, tags, packages, and distributes lipids/proteins</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Cytoskeleton</b></td><td style='border:1px solid #ddd; padding:4px;'>Maintains shape; secures organelles; movement</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td><td style='border:1px solid #ddd; padding:4px;'>Yes</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Flagella</b></td><td style='border:1px solid #ddd; padding:4px;'>Cellular locomotion</td><td style='border:1px solid #ddd; padding:4px;'>Some</td><td style='border:1px solid #ddd; padding:4px;'>No (except some sperm)</td></tr><tr><td style='border:1px solid #ddd; padding:4px;'><b>Cilia</b></td><td style='border:1px solid #ddd; padding:4px;'>Locomotion; movement of particles; filtration</td><td style='border:1px solid #ddd; padding:4px;'>Some</td><td style='border:1px solid #ddd; padding:4px;'>No</td></tr></table>

Animal vs Plant Cells

A phospholipid bilayer with embedded (integral) or attached (peripheral) proteins that separates the internal contents of the cell from its surrounding environment.

Plasma Membrane

The entire region between the plasma membrane and the nuclear envelope, consisting of organelles suspended in the gel-like cytosol, the cytoskeleton, and various chemicals.

Cytoplasm

The gel-like material of the cytoplasm in which cell structures are suspended.

Cytosol

The cell organelle that houses the cell’s DNA and directs the synthesis of ribosomes and proteins.

Nucleus

The double-membrane structure that constitutes the outermost portion of the nucleus.

Nuclear Envelope

The darkly staining body within the nucleus that is responsible for assembling ribosomal subunits.

Nucleolus

<b>Chromatin:</b> Protein-DNA complex that serves as the chromosomes' building material.<br><b>Chromosome:</b> Structure within the nucleus that comprises chromatin that contains DNA, the hereditary material.

Chromatin & Chromosomes

A cellular structure that carries out protein synthesis.

Ribosome

The cellular organelles responsible for carrying out cellular respiration, resulting in the production of ATP, the cell’s main energy-carrying molecule.

Mitochondria

A small, round organelle that contains hydrogen peroxide, oxidizes fatty acids and amino acids, and detoxifies many poisons.

Peroxisome

A plant cell organelle that carries out photosynthesis.

Chloroplast

A series of interconnected membranous structures within eukaryotic cells that collectively modify proteins and synthesize lipids.

Endoplasmic Reticulum (ER)

<b>Rough ER:</b> Studded with ribosomes; engages in protein modification.<br><b>Smooth ER:</b> Few or no ribosomes; synthesizes carbohydrates, lipids, and steroid hormones; detoxifies chemicals; stores calcium.

Rough ER vs Smooth ER

A eukaryotic organelle made up of a series of stacked membranes that sorts, tags, and packages lipids and proteins for distribution.

Golgi Apparatus

An organelle in an animal cell that functions as the cell’s digestive component; it breaks down proteins, polysaccharides, lipids, nucleic acids, and even worn-out organelles.

Lysosome

A membrane-bound sac, somewhat larger than a vesicle, that functions in cellular storage and transport.

Vacuole

A large plant cell organelle that acts as a storage compartment, water reservoir, and site of macromolecule degradation.

Central Vacuole

A small, membrane-bound sac that functions in cellular storage and transport; its membrane is capable of fusing with the plasma membrane and other membrane systems.

Vesicle

The network of protein fibers that collectively maintains the shape of the cell, secures some organelles in specific positions, allows cytoplasm and vesicles to move within the cell, and enables unicellular organisms to move.

Cytoskeleton

<b>Cilia:</b> Short, hair-like structures used to move an entire cell or substances along the outer surface.<br><b>Flagella:</b> Long, hair-like structures used to move the cell.

Cilia & Flagella

A rigid cell covering made of cellulose in plants, peptidoglycan in bacteria, non-peptidoglycan compounds in Archaea, and chitin in fungi that protects the cell, provides structural support, and gives shape to the cell.

Cell Wall

The material, primarily collagen, glycoproteins, and proteoglycans, secreted from animal cells that holds cells together as a tissue, allows cells to communicate, and provides mechanical protection.

Extracellular Matrix

<b>Plasmodesmata:</b> Channels between plant cell walls.<br><b>Tight Junctions:</b> Firm seals between animal cells.<br><b>Desmosomes:</b> Linkages between epithelial cells.<br><b>Gap Junctions:</b> Channels between animal cells for communication.

Intercellular Junctions

A model of the structure of the plasma membrane as a mosaic of components, including phospholipids, cholesterol, proteins, and glycolipids, resulting in a fluid rather than static character.

Fluid Mosaic Model

The characteristic of a membrane that allows some substances through but not others.

Selectively Permeable

A method of transporting material that does not require energy. Includes diffusion, osmosis, and facilitated transport.

Passive Transport

A passive process of transport of low-molecular weight material down its concentration gradient.

Diffusion

A process by which material moves down a concentration gradient (from high to low concentration) using integral membrane proteins.

Facilitated Transport

The transport of water through a semipermeable membrane from an area of high water concentration to an area of low water concentration across a membrane.

Osmosis

Water channel proteins that allow water to pass right through cell membranes.

Aquaporins

The pressure that must be applied to prevent osmotic movement across a selectively permeable membrane.

Osmotic Pressure

<b>Hypertonic:</b> Extracellular fluid has higher osmolarity than the cell (water moves out).<br><b>Hypotonic:</b> Extracellular fluid has lower osmolarity than the cell (water moves in).<br><b>Isotonic:</b> Extracellular fluid has the same osmolarity as the cell.

Tonicity

The method of transporting material that requires energy. Moves substances against their concentration gradient.

Active Transport

A gradient produced by the combined forces of the electrical gradient and the chemical gradient.

Electrochemical Gradient

A type of active transport that moves substances, including fluids and particles, into a cell. Includes <b>Phagocytosis</b> (cell eating) and <b>Pinocytosis</b> (cell drinking).

Endocytosis

A process of passing material out of a cell.

Exocytosis

Relatively constant internal physical and chemical conditions that organisms maintain.

Homeostasis

<b>Cell</b> -> <b>Tissue</b> (Group of similar cells) -> <b>Organ</b> (Group of tissues) -> <b>Organ System</b> (Group of organs).

Levels of Organization

On or in a cell, a specific protein to whose shape fits that of a specific molecular messenger, such as a hormone.

Receptor

Practice quiz

  1. A newly discovered single-celled organism possesses a cell wall, ribosomes, and a single circular chromosome, but lacks a nuclear envelope, mitochondria, and chloroplasts. Based on the Unified Cell Theory and cellular characteristics, which of the following statements is the most accurate conclusion about this organism?

    • It is a prokaryotic organism, and its cells are the basic unit of life, capable of synthesizing proteins and reproducing from existing cells.
    • It is a eukaryotic organism, as it contains ribosomes for protein synthesis, and its cells are the basic unit of life.
    • It is a eukaryotic organism that has lost its nucleus and mitochondria, but still adheres to the principle that new cells arise from existing cells.
    • It is a prokaryotic organism, but it violates the Unified Cell Theory because it lacks membrane-bound organelles.

    Answer: It is a prokaryotic organism, and its cells are the basic unit of life, capable of synthesizing proteins and reproducing from existing cells.

  2. An animal cell and a plant cell are both placed into separate beakers containing a solution that is significantly hypotonic relative to their internal cellular environments. Considering the structural differences between animal and plant cells, particularly regarding the cell wall and central vacuole, what is the most probable outcome for each cell?

    • The animal cell will undergo lysis, while the plant cell will become turgid due to the cell wall preventing excessive water intake and bursting.
    • Both the animal cell and the plant cell will swell and eventually lyse, as water rushes into both cells down its concentration gradient.
    • The animal cell will shrink due to water loss, while the plant cell will become flaccid as its central vacuole loses water.
    • Both the animal cell and the plant cell will become turgid, but only the plant cell's cell wall will prevent it from bursting.

    Answer: The animal cell will undergo lysis, while the plant cell will become turgid due to the cell wall preventing excessive water intake and bursting.

  3. A eukaryotic cell is genetically modified to produce a specific protein destined for secretion outside the cell. However, a mutation occurs that prevents the proper formation and budding of transport vesicles from the trans-Golgi network. Which of the following would be the most direct and significant consequence for the fate of this secreted protein and the cell's overall function?

    • The protein would accumulate in the Rough Endoplasmic Reticulum, leading to its degradation by peroxisomes.
    • The protein would be correctly synthesized and modified in the Golgi apparatus but would accumulate within the Golgi lumen, unable to be transported to the plasma membrane for exocytosis.
    • The protein would be misfolded in the cytoplasm and subsequently targeted to lysosomes for digestion, preventing its entry into the endomembrane system.
    • The protein would be secreted directly from the ribosomes into the extracellular matrix without any further modification or packaging.

    Answer: The protein would be correctly synthesized and modified in the Golgi apparatus but would accumulate within the Golgi lumen, unable to be transported to the plasma membrane for exocytosis.

  4. Consider a scenario where a cell's ability to maintain its electrochemical gradient across the plasma membrane is severely compromised due to a lack of ATP. This gradient is crucial for various cellular processes, including the active transport of ions. If the cell's mitochondria are non-functional, leading to a complete cessation of ATP production, what would be the most immediate and profound impact on the cell's homeostasis and its ability to perform active transport?

    • The cell would immediately begin to swell or shrink uncontrollably as passive transport mechanisms become unregulated, leading to a rapid loss of internal ion balance and eventual cell death.
    • The cell would switch to anaerobic respiration to produce ATP, maintaining the electrochemical gradient and continuing active transport without significant disruption.
    • Only facilitated diffusion would be affected, while other forms of passive and active transport would continue normally, as they do not directly rely on ATP.
    • The cell's internal environment would become isotonic with the extracellular fluid, eliminating the need for an electrochemical gradient and active transport.

    Answer: The cell would immediately begin to swell or shrink uncontrollably as passive transport mechanisms become unregulated, leading to a rapid loss of internal ion balance and eventual cell death.

  5. A plant cell is transferred from an isotonic solution to a hypertonic solution. Describe the sequence of events and the final state of the cell, emphasizing the roles of the plasma membrane, cell wall, and central vacuole in this process.

    • Water will move out of the cell, causing the central vacuole to shrink and the plasma membrane to pull away from the cell wall (plasmolysis), but the cell wall will maintain the overall shape of the cell.
    • Water will move into the cell, causing the central vacuole to expand and the plasma membrane to press against the cell wall, leading to increased turgor pressure and potential lysis.
    • The cell wall will prevent any water movement, maintaining the cell's original volume and shape, while the central vacuole remains unchanged.
    • The plasma membrane will become impermeable to water, and the cell will maintain its turgid state due to the rigidity of the cell wall.

    Answer: Water will move out of the cell, causing the central vacuole to shrink and the plasma membrane to pull away from the cell wall (plasmolysis), but the cell wall will maintain the overall shape of the cell.

  6. A novel drug is discovered that specifically targets and inhibits the polymerization of actin filaments, a key component of the cytoskeleton, within a eukaryotic cell. Considering the diverse functions of the cytoskeleton, which of the following cellular processes would be most directly and severely impaired by this drug, leading to significant functional disruption?

    • Protein synthesis on ribosomes and lipid synthesis in the Smooth Endoplasmic Reticulum.
    • The movement of vesicles and organelles within the cytoplasm, as well as changes in cell shape and cell division processes like cytokinesis.
    • ATP production in the mitochondria and detoxification of poisons by peroxisomes.
    • The modification, sorting, and packaging of proteins and lipids in the Golgi apparatus.

    Answer: The movement of vesicles and organelles within the cytoplasm, as well as changes in cell shape and cell division processes like cytokinesis.

  7. An epithelial tissue, such as the lining of the small intestine, requires both strong mechanical adhesion between cells to prevent leakage and efficient communication for coordinated absorption. Which combination of intercellular junctions and extracellular components would be most critical for enabling these specific functions?

    • Tight junctions to seal cells together and desmosomes for strong adhesion, along with gap junctions for rapid intercellular communication.
    • Plasmodesmata for communication and a thick cell wall for structural support, as seen in plant cells.
    • Gap junctions for mechanical strength and an extensive extracellular matrix of collagen for communication.
    • Only desmosomes for adhesion, as tight junctions would impede nutrient absorption, and communication is not essential.

    Answer: Tight junctions to seal cells together and desmosomes for strong adhesion, along with gap junctions for rapid intercellular communication.

  8. A large, polar molecule, such as glucose, needs to be transported into a cell from an area of lower concentration to an area of higher concentration. Given the properties of the plasma membrane as described by the Fluid Mosaic Model and its selectively permeable nature, which transport mechanism is absolutely required for this process?

    • Simple diffusion, as the plasma membrane is fluid and allows all molecules to pass through.
    • Facilitated diffusion, utilizing a carrier protein to move the molecule down its concentration gradient.
    • Active transport, involving a specific protein pump that uses energy (e.g., ATP) to move the molecule against its concentration gradient.
    • Osmosis, as water movement will indirectly pull the glucose molecules into the cell.

    Answer: Active transport, involving a specific protein pump that uses energy (e.g., ATP) to move the molecule against its concentration gradient.

  9. A scientist observes a eukaryotic cell under a microscope and notes the prominent presence of both mitochondria and chloroplasts. Based on the functions of these organelles and the characteristics of different cell types, what can be definitively inferred about this cell's metabolic capabilities and its likely classification?

    • This cell is capable of both photosynthesis and cellular respiration, indicating it is most likely a plant cell or an algal cell.
    • This cell is an animal cell that has recently engulfed a photosynthetic bacterium, and it primarily relies on cellular respiration for energy.
    • This cell is a prokaryote, as it possesses organelles for energy production, but lacks a true nucleus.
    • This cell can only produce ATP through photosynthesis and cannot perform cellular respiration.

    Answer: This cell is capable of both photosynthesis and cellular respiration, indicating it is most likely a plant cell or an algal cell.

  10. Consider a scenario where a cell's lysosomes are non-functional due to a genetic defect, preventing them from breaking down macromolecules and recycling worn-out organelles. How would this defect impact the cell's overall health and the function of other organelles within the endomembrane system?

    • The cell would accumulate waste products and damaged organelles, leading to cellular dysfunction and potentially cell death, while the Golgi apparatus and ER would become overloaded with unprocessed materials.
    • The cell would compensate by increasing the activity of peroxisomes to take over the digestive functions of the lysosomes, maintaining cellular homeostasis.
    • Protein synthesis would cease entirely, as ribosomes would lack the necessary components for assembly due to the inability to recycle amino acids.
    • The plasma membrane would become excessively permeable, leading to uncontrolled entry of substances and disruption of the cell's internal environment.

    Answer: The cell would accumulate waste products and damaged organelles, leading to cellular dysfunction and potentially cell death, while the Golgi apparatus and ER would become overloaded with unprocessed materials.

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